Wyatt DAWN HELEOS IIWebsite: Wyatt SEC-MALS GE AKTAPurifier UPC-10
A system for thorough absolute characterization of molecules
Wyatt Technology's DAWN HELEOS II is an 18-angle multi-angle light scattering (MALS) detector. It can assist in absolute characterization of molecules, including molecular weight, radius of gyration, conformation, second virial coefficient, and copolymer/protein conjugate analysis.
The HELEOS is compatible with most aqueous and organic solvents and can operate at temperatures from –15 to 150 degC. Detection ranges are ~1 kD to 1000 MDa (mass) and 10 to 500 nm (diameter).
The accompanying ASTRA software allows you to analyze your results in real-time
The instrument is connected in-line with an AKTApurifier UPC-10 FPLC system. This not only guarantees sample purity, but permits real-time monitoring of the composition of your sample as lower-weight components pass through the size-exclusion column more rapidly. Several size-exclusion columns are available for the system to suit your needs.
Also in-line with the HELEOS, Wyatt's Optilab T-rEX measures concentration, refractive index increment (dn/dc), and absolute refractive index.